To validate that c-Myc regulates ClpP expression in PCa cells, we performed a chromatin immunoprecipitation (ChIP) assay with an anti–c-Myc antibody, and observed reduced c-Myc binding to the ClpP promoter upon Hsp60 silencing (Figure 1, H and I). The gene discussed is HSPD1; the disease is posterior cortical atrophy.