Although PDPN was reported to interact with CLEC‐2 (C‐type‐lectin‐like‐2) to inhibit inflammation in sepsis,27 extra CLEC‐2 protein incubation had no effect on Il6 and Tnfa expression in Pam3CSK4‐stimulated PEMs during our study (Figure S5B). Here, PDPN is linked to Sepsis.