In alignment with evidence shown in Fig. 4, binding of the ITAFs PCBP2 and DHX9 (proteins with putative roles in translation initiation, but no known involvement in the innate antiviral defense), was not enhanced in A375 lysates primed with PVSRIPO infection (MOI 10, 48 hpi) (Fig. 5B). Here, DHX9 is linked to infection.