Fox example, dAurA383 treatment triggers the mitotic related processes such as “mitotic cell cycle,” echoing that dAurA383 arrests AML cells at mitosis by removing the spindle pool of AURKA, decreasing the phosphorylation of TACC3 and disrupting spindle microtubules.[59] However, dAurA383 treatment induces stemness related processes such as “CONRAD stem cell,” which is consistent with our finding that dAurA383 induces a population of CD34 high stem cells. This evidence concerns the gene AURKA and acute myeloid leukemia.