Our results support observation in the COSMIC Cell Lines Project (http://cancer.sanger.ac.uk) where amplifications of LAIR2, KLRC1, NCR1, NCR3, KLRC2, C3, and C4 were reported in various cancer cell lines such as lung carcinoma, adenocarcinoma, gastric choriocarcinoma, and pancreatic cancer cell lines. The gene discussed is C4A; the disease is familial pancreatic carcinoma.