TGFB1 and cancer: Thirdly and unexpectedly, we revealed that NK-cancer cell interaction triggered a new disparate role of TGFβ; instead of being immunosuppressive to NK cells, TGFβ sustained an increase in myosin light chain phosphorylation in NK cells, resulting in NK cell contractility which mediated Eomes nuclear localization leading to the enhancement of NK cytotoxicity.