To exclude that this effect was specific to HeLa cells, we generated RAD54L/RAD51AP1 single KO and DKO cells in the Hs578T breast cancer cell line [(Hackett et al., 1977); Supplementary Figure S1I; Supplementary Table S1] and tested these cells in olaparib cell survival assays. Here, RAD54L is linked to breast carcinoma.