The expression of PARP9 is controlled by the IFNγ-JAK2-STAT1-IFN regulatory factor 1 signaling pathway, which is essential for the survival of cells in diffuse large B-cell lymphoma (DLBCL), where the host inflammatory response is activated (Juszczynski et al., 2006). Here, IFNG is linked to diffuse large B-cell lymphoma.