In contrast, among subjects with diabetes, mRNA expression of TIMP1 and CXCL8 was significantly higher in subjects with PN (Figure 2), and positively correlated with MNSI-PE scores (rho = 0.469, p = 0.001; rho = 0.454, p = 0.002) (Figure 3). This evidence concerns the gene CXCL8 and diabetes mellitus.