According to previous publications, there have been a lot of research on the function of three genes NRAS (Dietrich et al., 2019; Ding et al., 2020), STMN1 (Zhang et al., 2020), and SLC1A5 (Zhao et al., 2021) in HCC, and in this study, our pre-experiment indicated the expression of MT3 didn’t affect the proliferation of HCC, so we focused on the role of FTL in HCC. The gene discussed is SLC1A5; the disease is hepatocellular carcinoma.