According to previous publications, there have been a lot of research on the function of three genes NRAS (Dietrich et al., 2019; Ding et al., 2020), STMN1 (Zhang et al., 2020), and SLC1A5 (Zhao et al., 2021) in HCC, and in this study, our pre-experiment indicated the expression of MT3 didn’t affect the proliferation of HCC, so we focused on the role of FTL in HCC. This evidence concerns the gene FTL and hepatocellular carcinoma.