The expression of BACH1 increases in Breast invasive carcinoma (BRCA p < 0.001), Kidney Chromophobe (KICH p < 0.001), Lung adenocarcinoma (LUAD, p < 0.0010), Lung squamous cell carcinoma (LUSC, p < 0.01), Uterine Corpus Endometrial Carcinoma (UCEC, p < 0.001) tumor tissue, and a decrease in Cholangiocarcinoma (CHOL, p < 0.050, Esophageal carcinoma (ESCA, p < 0.01), Glioblastoma multiforme (GBM, p < 0.010, Head and Neck squamous cell carcinoma (HNSC, p < 0.001), Stomach adenocarcinoma (STAD, p < 0.01) tumor tissues. The gene discussed is BACH1; the disease is head and neck squamous cell carcinoma.