VSIR and non-small cell lung carcinoma: Furthermore, scientists were able to localize the expression of the T cell inhibitory molecule VISTA in CD68+ macrophages of human pancreatic cancer (Blando et al., 2019) and retrieve information on the composition, expansion, and activity of TILs in patients with non-small cell lung cancer (NSCLC) (Sanmamed et al., 2021).