Shaver et al. found that the level of serum adiponectin in patients with uncomplicated diabetes was lower than that in normal subjects, and the level of adiponectin in patients with DCM was further decreased, suggesting that monitoring serum adiponectin may help with the diagnosis of early cardiomyopathy in patients with diabetes (Shaver et al., 2016). This evidence concerns the gene ADIPOQ and familial dilated cardiomyopathy.