The heat-map (Figure 8A) according to the correlation between RCN3 and multiple immunoinhibitory molecules including TIGIT, TGFB1, PDCD1LG2, PDCD1, NECTIN2, LGALS9, LAG3, IL10RB, IL10, HAVCR2, CTLA4, CSF1R, CD96, BTLA, and ADORA2A in pan-cancer suggested that most correlations were positive. The gene discussed is IL10RB; the disease is cancer.