PTBP1 was also reported to regulate the phosphatase and tensin homolog-phosphatidylinositol-4,5-bisphosphate 3-kinase/protein kinase B (PTEN-PI3K/Akt) pathway and autophagy, thus inducing the proliferation, invasion, and metastasis of breast cancer cells [39]. The gene discussed is PTBP1; the disease is breast carcinoma.