NRP2 and lung carcinoma: Recently, we demonstrated in lung cancer cells that the pro-tumorigenic activity of NRP2 resides primarily in the NRP2b isoform, which is upregulated during TGFβ-induced epithelial-mesenchymal transition (EMT) and is associated with more advanced stage, increased metastasis, and resistance to tyrosine kinase inhibitors (8, 9).