In addition, we observed that at the peak of infection pro-inflammatory markers Ifnb and Il6 (Figures 1E, F) were significantly upregulated in lesions of Nlrx1-/- mice infected with LgyLRV1+ parasites, while no differences were observed in Tnfa expression as measured by qRT-PCR (Figure 1G). The gene discussed is IL6; the disease is infection.