Considering the significant parts of CCAT1 in the development of cancer and the unclear effects of CCAT1 in lung cancer, we implemented a case–control study to analyze the relationship of the polymorphisms rs1948915, rs7013433 in lncRNA CCAT1 and rs6983267 in the MYC enhancer region with lung cancer susceptibility in the northeast of China. The gene discussed is MYC; the disease is lung cancer.