On the other hand, the expression of FAM83A, FAM83D, FAM83E, FAM83F, and FAM83G was significantly higher in breast cancer tissues than in normal tissues (P = 0.043, Fig. 2A; P < 0.001, Fig. 2D; P = 0.004, Fig. 2E; P < 0.001, Fig. 2F; P = 0.016, Fig. 2G). The gene discussed is SACK1D; the disease is breast carcinoma.