For FAM83F, we got the typical immunohistochemical positive pictures of FAM83F in breast cancer patients’ specimens, its subcellular location (mainly enriched in mitochondria and nucleoplasm), the FAM83F mRNA level of different cell lines ordered by organ of phenotypic resemblance, immunofluorescence staining result of FAM83F in U-2 OS cells. The gene discussed is SACK1F; the disease is breast cancer.