Previous studies had shown that the altered expression of genes include MAOB (monoamine oxidase B)248, VEGFC (vascular endothelial growth factor C)249, DBP (D-box binding PAR bZIP transcription factor)250, MYADM (myeloid associated differentiation marker)251, NES (nestin)252, SMURF1253, EDNRB (endothelin receptor type B)254, MUC6255, TOR2A256, TNKS (tankyrase)257, NEDD9258, ASIC1259, ADAMTS8260, DYSF (dysferlin)261, SLC26A9262, SLC45A3263 and KCNQ2264 were closely related to the occurrence of hypertension. Here, NES is linked to hypertensive disorder.