Together, RNPS1, MAPK3, NEK6, hsa-mir-4677-3p, hsa-mir-3125, hsa-mir-4779, hsa-mir-548az-3p, hsa-mir-5688, hsa-mir-6512-3p, XAB2, KHDRBS1 and RELA might be effective targets in T1DM, but more experimental investigations and clinical trials are needed. Here, RNPS1 is linked to type 1 diabetes mellitus.