In vivo assays of the kidney after unilateral ureteric obstruction (UUO) and nephrotoxic serum (NTS) administration suggest that NLRP6 is dispensable after kidney injury, given that no phenotype is observed in Nlrp6−/− mice and no Nlrp6 protein is detectable in the kidney24. The gene discussed is NLRP6; the disease is Ureteral obstruction.