In the reviewed reports, gustatory dysfunction (dysgeusia/hypogeusia) was present either as the sole oral manifestation or associated with xerostomia and/or burning mouth sensation in 69.8 percent of the patients (Fig 2) In a recent report, Huang et al., using single-cell RNA (scRNA) analyses, elegantly illustrated the rich expression of ACE2 and transmembrane serine protease (TMPRSS) receptors for SARS-CoV-2 in the acinar and duct epithelial cells of both the major and minor salivary glandular tissue derived from COVID-19 patients [5]. The gene discussed is ACE2; the disease is COVID-19.