ITGA5 and familial pancreatic carcinoma: Examination of the relationship between gene expression and prognosis using the R2 platform showed that ITGB1 was significantly correlated with the prognosis of pancreatic cancer (p = 0.036), but COL4A1 (p = 0.084), COL4A2 (p = 0.121), and ITGA5 (p = 0.285) were not (Fig 2).