Indeed, in patients with PF, TGF-β1 is involved in myofibroblast differentiation from fibroblasts, and α-smooth muscle actin (α-SMA)-expressing differentiated myofibroblasts mediate the production of ECM components, integrins, protease inhibitors, regulators of small GTPases, and MMPs. Here, TGFB1 is linked to pemphigus foliaceus.