First, we need to deal with synonyms, for example “diabetes type 2,” “T2D” (type 2 diabetes) and (see Figure 12) “diabetes mellitus, insulin dependent.” Symbols, including both natural language terms and identifiers referring to this disease, as a “mental construct” should, although referred to by many synonyms and multiple “uris” in multiple thesauri, always resolve to the intended defined meaning. This evidence concerns the gene INS and type 2 diabetes mellitus.