Walz et al. [40] reported that the morphological feature of confluent necrosis in ACC is universal, while the benign adrenocortical adenomas (ACN) completely lack this kind of highly reproducible feature; what is more, the Ki67 levels above 10% were found in more than 96.8% ACC samples and never in ACNs. The gene discussed is MKI67; the disease is adrenal cortex adenoma.