Factors positively associated with the development of AF in both ventilated and non-ventilated cohorts include immunoinflammatory markers such as increased average CRP (OR: total = 1.281, ventilated = 1.384, non-ventilated = 1.312) in multivariate analysis, as well as average APTT (OR: total = 1.133, ventilated = 1.150) in the ventilated cohort. Here, CRP is linked to atrial fibrillation.