The ability of TXNRD1 levels to diagnose IPAH was assessed using ROC curve analysis which showed that the sensitivity and specificity were 92.3 and 66.7%, respectively, at the optimal expression cutoff value of 0.60, and AUC value of 0.795 exhibited great predictive efficiency of TXNRD1 as diagnosis biomarker (Figure 5C). This evidence concerns the gene TXNRD1 and idiopathic pulmonary arterial hypertension.