SOAT1 and cancer: A similar analysis was carried out for the other six essential pathways—hematopoietic cell lineage, metabolism of xenobiotics by cytochrome p450, drug metabolism cytochrome p450, JAK-STAT signaling pathway, Leishmania infection, and pentose and glucuronate interconversions; as a result, BSG expression primarily showed negative correlations with leading-edge genes of the six signaling pathways (p < 0.05; Supplementary Figures S8B–G), indicating the roles of BSG played in specific cancers may be due to the disorder of these pathways.