Furthermore, ischemic stroke has 14 similar pathogenetic genes, ACVRL1, APP, ABCC6, CST3, ENG, F7, JAK2, PLAT, PLAU, VHL, SH2B3, PDCD10, KIF1B, and CCM2, and has 48 similar signaling pathways to hemorrhagic stroke, whereas the stroke-related ID C0553692 is related to hemorrhagic stroke and to 29 pathogenetic genes and 48 signaling pathways. The gene discussed is SH2B3; the disease is ischemic stroke.