To this aim, activated PBMCs were infected ex vivo by spinoculation with NL4.3-Renilla or an Env-deficient HIV (NL4.3Δenv-Renilla) pseudotyped with the envelope of Stomatitis Vesicular Virus (VSV) and the intracellular expression of MxA, an IFN-stimulated gene, was measured 5 days post-infection. The gene discussed is ERVW-1; the disease is infection.