TP53 and neoplasm: Moreover, p53 governs not only tumor suppression, but also many aspects of cellular functions including DNA repair (Sengupta and Harris, 2005; Williams and Schumacher, 2016), cell cycle arrest (Chen, 2016) and apoptosis (Aubrey et al., 2018) etc. This topic is too broad to be covered in one section and many of these topics have been separately reviewed elsewhere.