SREBPs transcriptionally activates enzymes involved in lipogenesis processes in cancer cells (Liu et al., 2017), including ATP citrate lyase (ACLY), acetyl-CoA carboxylase (ACC), fatty acid synthase (FASN), and acyl-CoA synthetase (ACS) which play significant roles in the process of lipid biosynthesis (Currie et al., 2013) (seen Figure 2). This evidence concerns the gene ACLY and cancer.