Ubiquitination is a post-translational modification that controls multiple steps in autophagy, a major lysosome-mediated intracellular degradation pathway (Grumati and Dikic, 2018) and several of the selected genes share ubiquitin functions by Gene Ontology including CBLB (Casitas B-Lineage Lymphoma Proto-Oncogene B), USP17L24 (Ubiquitin Specific Peptidase 17 Like Family Member 24), and USP19 (Ubiquitin Specific Peptidase 19). This evidence concerns the gene USP17L24 and lymphoma.