C1 had a shorter median survival time, higher cell cycle, RTK, RAS, WNT, and angiogenesis pathway activation scores and the pathway predominantly affected in this subtype was the inositol phosphate metabolism pathway, and the inositol phosphate metabolism pathway involved in cell proliferation, migration and phosphatidylinositol-3-kinase (PI3K)/Akt signaling, play a crucial in cancer and are frequently dysregulated in cancer (27). The gene discussed is AKT1; the disease is cancer.