Combined with various drugs, paclitaxel could inhibit the proliferation and migration of tumor cells through promoting the secretion of immune factors, regulating the expression of EMT-related proteins, down-regulating the expression of N-Cadherin, β-Catenin and Vimentin, and up-regulating the expression of epithelial marker proteins E-Cadherin, Claudin-1 and ZO-1 (47, 48). This evidence concerns the gene CDH2 and neoplasm.