Tanshinone IIA inhibited the proliferation and promoted apoptosis of human gastric cancer cell lines SNU-638, MKN1, and AGS cells, which was attributed to inhibiting the phosphorylation of STAT3 to downregulate Bcl-2, and upregulate Bax, and cleaved caspase-3 (70). This evidence concerns the gene BCL2 and gastric cancer.