COL6A1 and neoplasm: Coincidently, a non-significant decrease in EJ, and an increase in COL6A1, in the 5637 cell line, compared with the SV-HUC-1 cell line, may be understood with the conjecture that collagen VI promotes tumor growth with expression variation in the ECM (40), likely promoting differences in expression between tumor tissue and tumor cell lines (41, 42).