ZC3HC1 and thymus lymphoma: Thus, as it has been shown previously that Nipa deficiency significantly reduces hematopoietic stem cell frequency after replication stress due to impaired DNA damage repair followed by apoptosis (35), we analyzed thymic lymphomas of Lck/CreTG/wtNipawt/wt and Nipaflox/flox MSNAIE transplanted mice for stem cell markers.