The KEAPSAKE trial examines the efficacy of the same glutaminase inhibitor – telaglenastat – combined with the standard-of-care pembrolizumab and chemotherapy in NSCLC patients mutated in KEAP1 using STK11/LKB1 status for the stratification (https://clinicaltrials.gov). The gene discussed is STK11; the disease is non-small cell lung carcinoma.