Investigating the effects of LKB1 on the tumor microenvironment, they found that its inactivation promoted greater expression of neutrophil-recruiting chemokines such as CXCL7 and CXCL5 and pro-inflammatory cytokines such as IL-6, which contributes to neutrophil accumulation in NSCLC models. This evidence concerns the gene STK11 and non-small cell lung carcinoma.