Depletion of G-MDSCs obtained using anti-Gr-1 antibody or all-trans retinoic acid (ATRA) had the result of reversing the immune suppression and sensitized LKB1-deficient tumors to immunotherapy, suggesting that ATRA therapy might offer useful strategy to overcome immune resistance in NSCLC deleted in LKB1 (179). Here, STK11 is linked to non-small cell lung carcinoma.