S100A8 and cancer: S100A8 mRNA expression substantially differed in cancer samples from BRCA, CESC, ESCA, GBM, HNSC, KICH, KIRC, KIRP, LIHC, LUAD, PRAD, STAD, and UCEC, showing that S100A8 may operate as an oncogene in the advancement of several malignancies (Figure 3(a)).