Some genes are associated with metabolic processes, such as glucose transporter 1 (SLC2A1, also known as GLUT1), which encodes a key rate-limiting factor in glucose transport into cancer cells, and thioredoxin reductase 1 (TXNRD1), which is the cytosolic subunit and key enzyme of the thioredoxin system. The gene discussed is SLC2A1; the disease is cancer.