PPARA and Cushing syndrome due to macronodular adrenal hyperplasia: Moreover, KEGG pathway analysis suggested that DEGs were mainly involved in human papillomavirus infection (Blay et al., 2020), Cushing syndrome, small-cell lung cancer, AGE−RAGE signaling pathway in diabetic complications, amebiasis, ECM−receptor interaction, PPAR signaling pathway, steroid hormone biosynthesis, and bladder cancer (Figure 4).