For the results of KEGG enrichment analysis, most of these pathways are related to immunity, and we want to highlight HLA-C, HLA-A and GZMB, because these genes were obtained in several immune-related KEGG pathways (“Type I diabetes mellitus”, “Allograft rejection”, “Graft-versus-host disease”, “Autoimmune thyroid disease”, “Natural killer cell mediated cytotoxicity”). The gene discussed is GZMB; the disease is type 1 diabetes mellitus.