DHX30 has also been found to bind to the CCG repeats of FMR1 and depleting DHX30 levels in a Drosophila model reduced CGG repeat toxicity, potentially implicating it in FXTAS microsatellite disorder however further studies are required to confirm this association (Malik et al., 2021). This evidence concerns the gene DHX30 and fragile X-associated tremor/ataxia syndrome.