EPHB2 and neoplasm: lncRNA TCONS_00367775, TCONS_00323331, and TCONS_00204925 were predicted to regulate the miRNAs, thus suppressing the expression of ITGA6, HSPH1, MAPK3, EPHB2, and COL1A1. The target gene Itga6 encodes a peptide chain that is one of the subunits of the integrin family and which is closely associated with the ECM receptor signaling pathway; moreover, ITGA6 has been found to be associated with cell proliferation and cell motility in tumor-related studies (Muir et al., 2020).