IL12RB1 and colorectal cancer: In this study, we investigated for the first time the association between two single nucleotide polymorphisms (SNPs) within the IL-12RB1 gene, namely, IL-12RB1 +1196G/C (G378R, NCBI SNP ID: rs401502) and IL-12RB1 +705A/G (Q214R, NCBI SNP ID: rs11575934), and the colorectal cancer susceptibility in a Tunisian cohort.