NOTCH1 and diffuse large B-cell lymphoma: At the molecular level, DLBCL can be divided into four genetic subtypes with different outcomes, including MCD (based on the co-occurrence of MYD88L265P and CD79B mutations), BN2 (based on BCL6 fusions and NOTCH2 mutations), N1 (based on NOTCH1 mutations), and EZB (based on EZH2 mutations and BCL2 translocations).