Another study showed that small nucleolar RNA host gene 20 (SNHG20) played the oncogenic role through enhancing the growth and metastasis of ESCC through the ataxia telangiectasia-mutated kinase (ATM)-JAK-programmed cell death 1 ligand 1 (PD-L1) axis (Zhang et al., 2019a). Here, CD274 is linked to esophageal squamous cell carcinoma.