Song et al. (2020) also found that BANCR can promote the malignant behaviors of ESCC and BANCR downregulation inhibited the ESCC development by inactivating the insulin like growth factor 1 receptor (IGF1R)/Raf/MEK/ERK axis by sponging the miR-338-3p. Here, MAPK1 is linked to esophageal squamous cell carcinoma.