NONO and esophageal squamous cell carcinoma: Zhu et al. (2021) found that lncRNA FAM225A facilitated the ESCC development through sponging miR-197-5p, thus upregulating the non-POU domain-containing octamer-binding protein (NONO) expression and activating the transforming growth factor-β (TGF-β) pathway in ESCC cells.