HMOX1 and acute myeloid leukemia: AS shown in Figure 7C, compared with honokiol treated group, the cell viability of honokiol combined with ZnPP treated group was significantly increased (**, p < 0.01), suggesting that HMOX1 inhibitor ZnPP can rescue the ferroptosis of AML cells and HMOX1 is a necessary molecule to induce ferroptosis in AML cells induced by honokiol.