Imatinib treatment significantly increased IMI and IV in female (1.7-fold) (p ≤ 0.0001; Figures 2B,D, 4A–D) and male (1.6-fold) (p ≤ 0.05; Figures 2C,E) mice with acute CYP-induced cystitis. The gene discussed is PPIG; the disease is chronic cystitis.